A systematic review and meta-analysis evaluating the efficacy and safety of MRI‑guided focused ultrasound lesioning to reduce tremor in patients with tremor‑dominant Parkinson disease.

This paper is clinically relevant and translational—summarizing evidence for a non‑pharmacologic, device‑based symptomatic therapy that can inform patient selection, safety profiles, and trial design—though it offers limited insight into disease‑modifying mechanisms.