PURPOSE OF REVIEW: This review examines the potential role of coconut-derived nutritional supplements in influencing Parkinson's disease risk and progression by modulating oxidative stress and mitochondrial function. Parkinson's disease is a neurodegenerative disease characterized by the death of dopaminergic neurons, mitochondrial damage, and increased oxidative stress. Nutritional approaches have garnered attention as adjunctive therapeutic strategies. RECENT FINDINGS: The natural products of coconut, including coconut oil, coconut milk, coconut water, and coconut kernel, are rich in fatty acids, antioxidants, vitamins, and other essential minerals, which can have neuroprotective effects. Additionally, evidence suggests an inverse correlation between coconut consumption and the PD prevalence. Consequently, nutrients obtained from coconut products represent promising natural neuroprotective agents for the prevention and management of PD. Further studies ought to focus more on clinical trials to confirm the effectiveness of coconut-based supplements and explain the underlying neuroprotective effects of these supplements in the management of PD.