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Active intelligence prompt Pediatric cancer: surface high-value therapeutic signals across pediatric oncology literature.
PEDIATRIC CANCER RESEARCH INTELLIGENCE

Finding therapies hidden in 37,335 pediatric cancer papers.

Neurocompute scores pediatric oncology literature, surfaces overlooked therapeutic signals, and turns fragmented childhood cancer research into a living discovery terminal.

37,335 Papers indexed
371 Papers AI scored
37,335 Ranked papers
100.0% Coverage
PATIENT-FRIENDLY SUMMARY

CHIP-AML22: a complex clinical trial in de novo pediatric AML patients, including a gemtuzumab ozogamicin randomization and targeted therapy with quizartinib in eligible subgroups, within the NOPHO-DB-SHIP consortium.

For education only—not personal medical advice.

LIVE PEDIATRIC ONCOLOGY INTELLIGENCE
↑ Therapeutic signals emerging ↑ New pediatric cancer papers ingested ↑ Cross-paper convergence detected ↑ Human relevance scores updating ↑ Overlooked treatment paths surfacing
TOP PEDIATRIC CANCER SIGNALS

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LATEST PEDIATRIC CANCER PAPERS

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Last ingest 2026-08-26 09:15 AM
1 Thyroid-stimulating hormone-secreting pituitary neuroendocrine tumor (TSH-PitNet) diagnosed during pregnancy and treated with a somatostatin analog. Taiwanese journal of obstetrics & gynecology 47.5 Aug 26, 2026 2 Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study. The Lancet. Oncology 85.2 Aug 26, 2026 3 Breast disorders in adolescence: Etiological, clinical, and therapeutic aspects. Archivos argentinos de pediatria 62.64 Aug 26, 2026 4 MicroRNA profiles as diagnostic tools in pediatric acute lymphoblastic leukemia. Clinica chimica acta; international journal of clinical chemistry 63.0 Aug 26, 2026 5 Somatic mutations in human ontogenesis and their impact on health. Ageing research reviews 40.0 Aug 26, 2026 6 Methylation profile scores in child and adolescent health: a practical guide. The Lancet. Child & adolescent health 61.1 Aug 26, 2026 7 On-demand transarterial chemoembolisation combined with atezolizumab and bevacizumab in patients with untreated hepatocellular carcinoma (TALENTACE): a multicentre, randomised, open-label, phase 3 trial. The lancet. Gastroenterology & hepatology 84.4 Aug 26, 2026 8 Cryoablation of Malignancies and Aggressive Benign Diseases in Children: Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel. Journal of vascular and interventional radiology : JVIR 64.7 Aug 26, 2026
PEDIATRIC CANCER RESEARCH TERMINAL

All ranked pediatric cancer papers

37335 results
C
Young Women Diagnosed With Breast Cancer: Why Is No One Telling Me to Get a Mammogram?
PMID 42574085 Published: 2026-09-01 Ingested: 2026-08-17 12:23 AM Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
AI 27.40
Base 61.9
Rank 46.38
AI Summary

In qualitative interviews with 30 women diagnosed with breast cancer before age 40, the study identified themes involving symptom discovery, diagnosis, family communication, treatment decisions, and fertility, while reporting common diagnostic delays and unmet age-specific care needs.

Why It Matters

The evidence supports a need to investigate patient-, provider-, and system-level contributors to delayed diagnosis in young women; it can be inferred—but is not demonstrated here—that targeted awareness, diagnostic pathways, or age-specific supportive care could reduce delays and improve care experiences, while the study does not establish a benefit from routine mammography before age 40.

C
AI 30.30
Base 59.0
Rank 46.09
AI Summary

A cross-sectional survey of 137 pediatric oncology providers at a Jordanian cancer center found high perceived importance of qualitative research but low objective knowledge, with lack of time and training as common barriers and strong interest in workshops and mentorship.

Why It Matters

The evidence identifies a provider-level capacity gap rather than a therapy; it supports the inference that structured qualitative-research training and mentorship could improve incorporation of patient and caregiver perspectives into care delivery, but no intervention, patient outcome, or cancer-treatment benefit was tested.

C
Outcomes of minimally invasive pit-picking treatment in adolescents with uncomplicated pilonidal disease: a retrospective single-center study.
PMID 42593573 Published: 2026-08-13 Ingested: 2026-08-17 12:23 AM Pediatric surgery international
AI 25.10
Base 63.24
Rank 46.08
AI Summary

In a retrospective single-center cohort of 42 adolescents with uncomplicated pilonidal disease treated by pit-picking, recurrence occurred in 14.3% over a median 15-month follow-up and was more frequent with multiple sinus openings.

Why It Matters

The record supports pit-picking as a clinically used, minimally invasive surgical option for selected adolescents with uncomplicated pilonidal disease; it suggests—but does not establish—that sinus-opening number could inform patient selection, and it provides no pediatric-oncology therapeutic hypothesis.

D
AI 41.30
Base 49.9
Rank 46.03
AI Summary

This case report describes an 11-year-old boy with H3K27M-mutant DLGNT, coexisting BRAF-KIAA1549 fusion, and diffuse leptomeningeal spread presenting as communicating hydrocephalus initially misdiagnosed as idiopathic intracranial hypertension, followed by rapid fatal progression.

Why It Matters

The report establishes no therapeutic efficacy; it supports the clinical inference that early neuroaxis imaging and molecular characterization in unexplained pediatric communicating hydrocephalus could accelerate DLGNT diagnosis, while the BRAF-KIAA1549 fusion may warrant future investigation as a treatment-selection biomarker despite the concurrent H3K27M mutation.

C
Health Risk Assessment of Cadmium in Brazilian Makeup Products Using a Novel MDSPE-FAAS Method.
PMID 42597986 Published: 2026-07-29 Ingested: 2026-08-17 12:23 AM ACS omega
AI 30.50
Base 58.7
Rank 46.01
AI Summary

The study validated an Fe3O4@TEOS-based MDSPE-FAAS method and found cadmium in 16 of 29 Brazilian makeup products, with modeled lifetime cancer risk above acceptable limits in cadmium-positive samples and higher estimated risk for children's products.

Why It Matters

The evidence supports using the analytical method to identify cadmium-contaminated cosmetics; it is an inference, not directly tested here, that enhanced surveillance, manufacturing controls, or regulation could reduce pediatric cadmium exposure and potentially lower long-term cancer risk.

D
Surgical Excision of a Rare Ventral Scapular Osteochondroma using the Prone "Chicken-Wing" Position: A Case Report.
PMID 42597661 Published: 2026-08-01 Ingested: 2026-08-17 12:23 AM Journal of orthopaedic case reports
AI 46.40
Base 45.5
Rank 45.91
AI Summary

This case report describes complete posterior surgical excision of a ventral scapular osteochondroma in a 10-year-old boy positioned prone in a "chicken-wing" configuration, with reported relief of mechanical symptoms and excellent functional recovery.

Why It Matters

The reported case supports that complete excision can relieve symptoms caused by mechanical scapulothoracic impingement; it is plausible, but not established, that the prone "chicken-wing" position improves surgical exposure or safety compared with other approaches.

C
Temporal trends in hospitalization due to pediatric thyroid cancer in Chile: a population-based analysis from 2001 to 2024.
PMID 42599836 Published: 2026-08-14 Ingested: 2026-08-17 12:23 AM Hormone research in paediatrics
AI 28.70
Base 59.9
Rank 45.86
AI Summary

This national registry analysis reports that pediatric thyroid cancer hospitalization rates in Chile increased from 0.48 to 2.46 per 100,000 between 2001 and 2024, primarily among adolescents, alongside increased surgical management and stable median length of stay.

Why It Matters

The evidence supports an age-specific rise in thyroid cancer-related hospitalizations and surgical management, but no therapy was evaluated; as an inference, these trends could guide adolescent-focused diagnostic, referral, and health-service strategies, which would require studies linking hospitalization data to incidence, treatment quality, and outcomes.

C
Survival of U.S. Military Service Members with Hodgkin Lymphoma by Post 9/11 Deployment Status.
PMID 42574494 Published: 2026-08-10 Ingested: 2026-08-17 12:23 AM Cancer research communications
AI 29.10
Base 59.12
Rank 45.61
AI Summary

In a registry-based cohort of 752 U.S. service members with classic Hodgkin lymphoma, post-9/11 deployment was not significantly associated with overall or disease-specific mortality, while service members had lower adjusted mortality than SEER comparators.

Why It Matters

The study provides no direct evidence for a therapy; it supports the inference that healthcare access, survivorship support, or other military-system factors may contribute to favorable outcomes and merit prospective study as care-delivery interventions.

C
Increasing Rate of Pott's Puffy Tumor Hospitalizations Among US Children.
PMID 42595347 Published: 2026-08-14 Ingested: 2026-08-17 12:23 AM Hospital pediatrics
AI 26.80
Base 59.5
Rank 44.79
AI Summary

This cross-sectional Epic Cosmos study reports that pediatric Pott's puffy tumor hospitalizations increased from 2.8 to 6.0 per 100,000 hospitalizations between 2017 and 2025, alongside an increase in surgical procedures from 37% to 60%.

Why It Matters

The evidence establishes an epidemiologic and management trend, not a therapeutic effect; it may indirectly support earlier recognition and investigation of changing surgical-management needs, but no treatment-selection, efficacy, safety, or pediatric-oncology hypothesis was tested.

C
Imaging Evaluation of Pediatric Supratentorial Tumors: Pearls and Pitfalls.
PMID 42594025 Published: 2026-09-01 Ingested: 2026-08-17 12:23 AM Radiographics : a review publication of the Radiological Society of North America, Inc
AI 27.60
Base 58.8
Rank 44.76
AI Summary

This review describes how patient age and MRI features can help narrow the differential diagnosis of pediatric supratentorial tumors and notes that molecular alterations may inform diagnosis and prognosis.

Why It Matters

The record supports imaging-based diagnostic stratification rather than a therapeutic intervention; as an inference, more accurate integration of imaging, age, and tumor genetics could improve treatment selection and surgical planning, but no comparative or outcome evidence is provided.

C
Radiological characterization of drinking water sources in copper belt, Aravalli hill and mining-affected regions of Northern Rajasthan.
PMID 42571750 Published: 2026-08-06 Ingested: 2026-08-17 12:23 AM Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
AI 29.10
Base 57.2
Rank 44.56
AI Summary

The study measured dissolved radon-222 in 200 groundwater and tap/storage-water samples from mining-affected regions of Northern Rajasthan and estimated age-specific ingestion and inhalation doses, reporting particularly high concentrations in deep groundwater and calculated doses above WHO drinking-water guidance limits.

Why It Matters

The evidence identifies potentially preventable environmental radon exposure, including calculated doses for children; it is reasonable to infer that water-source management or radon-removal measures could reduce exposure, but the study did not test mitigation, cancer prevention, treatment, or clinical outcomes.

C
Chronic pain among patients treated for breast cancer: Prevalence and associates factors.
PMID 42578774 Published: 2026-05-01 Ingested: 2026-08-17 12:23 AM La Tunisie medicale
AI 28.30
Base 57.5
Rank 44.36
AI Summary

This cross-sectional study of 100 Tunisian women treated surgically for breast cancer reports chronic pain in all participants and identifies body mass index, number of children, and number of lymph nodes removed as independent correlates of pain intensity.

Why It Matters

The evidence supports these variables as associations with pain intensity in this cohort; it may be inferred—but was not tested—that risk-stratified pain screening and comprehensive supportive-care management could improve survivorship outcomes.

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