RESEARCH PAPER ANALYSIS
Spectrum of metastatic tumours to orbit over the last twenty years in a tertiary care eye hospital-A retrospective study.
AI interpretation is pending for this paper.
Open original publication →EXECUTIVE SUMMARY
What the AI sees
Not AI summarized yet.
WHY IT MATTERS
Research significance
Pending deeper interpretation.
ABSTRACT
Source abstract
OBJECTIVE: To assess the type and presentation patterns of tumours metastasising to orbit. METHODS: The retrospective study was conducted at the Al Shifa Trust Eye Hospital, Rawalpindi, Pakistan, and comprised data of all patients with orbital metastatic lesions over a 20-year period, from January 1, 2004, to December 31, 2023. Data was analysed using SPSS 22. RESULTS: Of the 30 patients, 17(56.7%) were males and 13(43.3%) were females. The highest incidence of orbital metastatic disease was among those aged <10 years 9(30%) and >60 years 11(36.7%). Roof was the commonest site of involvement within the orbit 13(43.3%). Proptosis was the main feature at presentation. Diagnosis was made clinically in 14(46.7%) patients and histologically in 16(53.3%). All the 30(100%) cases were referred to the oncology service for further management. Of them, 2(6.7%) patients were lost to follow-up, 20(66.7%) died within one year of diagnosis, and 8 (26.6%) patients were still under treatment. CONCLUSIONS: The diagnosis of orbital metastasis should always be considered for orbital lesions in all age groups, especially in patients with a known cancer elsewhere. Orbital metastasis usually becomes evident at an advanced stage of underlying malignancy, leading to a high mortality rate..
SUPPORTING PAPER SET
32 more papers to review
1
When Diagnosis Is Not Enough: Management Challenges and Outcomes of CNS Tumours in Children Under Three Years in the Largest Public-Sector Center in Pakistan.
JPMA. The Journal of the Pakistan Medical Association
69.5
2
Endoscopic Endonasal Versus Endoscopic Supraorbital Keyhole Surgery for Craniopharyngioma Resection: A 15-Year Single-Center Retrospective Cohort Study.
JPMA. The Journal of the Pakistan Medical Association
66.0
3
Incidence and Molecular Marker Association with Drop Metastases in Ependymoma Patients -A 25-year Experience from a Tertiary Care Center.
JPMA. The Journal of the Pakistan Medical Association
76.6
4
Ten year retrospective cohort of primary Intracranial Germ cell tumour in children adolescents and young Adults at a tertiary centre in a Low- to middle- Income country: Prevalence, Treatment, and Outcomesn.
JPMA. The Journal of the Pakistan Medical Association
75.84
5
Clinical Outcomes and Prognostic Factors Following Surgery for Supratentorial Intraventricular Tumours: A 15-year Experience.
JPMA. The Journal of the Pakistan Medical Association
69.4
6
Age and Sex-Specific Provincial Patterns of Brain and CNS Cancer Mortality in Pakistan: A Global Burden of Disease Study.
JPMA. The Journal of the Pakistan Medical Association
38.5
7
Transcriptomic Analysis Identifies the PVT1-miR-34a Axis as a Novel Non-Coding RNA Therapeutic Target in Diffuse Intrinsic Pontine Glioma.
JPMA. The Journal of the Pakistan Medical Association
67.74
8
Quantifying the surgical mediation of income-based survival disparities in glioblastoma: a SEER causal four-way decomposition (2007-2022).
JPMA. The Journal of the Pakistan Medical Association
67.12
9
Preoperative identity Threat and Illness Perception in Patients Undergoing Resection of Intracranial Tumours: A Multidimensional Cross-sectional Study Using Validated Psychometric Instruments.
JPMA. The Journal of the Pakistan Medical Association
63.4
10
Childhood and Adolescent Central Nervous System Tumour Mortality in the United States, 1999- 2024: A CDC WONDER Joinpoint Analysis and Surveillance Model for Pakistan.
JPMA. The Journal of the Pakistan Medical Association
57.5
11
Paediatric Scalp Squamous Cell Carcinoma With Suspected Intracranial Extension Mimicking Cerebral Abscesses in a Patient With Xeroderma Pigmentosum: A Case Report and Literature Review Abstract.
JPMA. The Journal of the Pakistan Medical Association
49.9
12
Recurrence to persistence: Inflammatory markers in pediatric rheumatic heart disease.
Annals of pediatric cardiology
58.5
13
Prevalence and genotype distribution of human papillomavirus (HPV) among adolescent girls and young women in a high HIV burden rural area of South Africa: a cross-sectional survey.
medRxiv : the preprint server for health sciences
61.0
14
Delayed B-cell reconstitution in the bone marrow precedes the development of chronic graft-versus-host disease following pediatric hematopoietic stem cell transplantation.
Frontiers in immunology
61.7
15
Parental and childhood exposures and the risk of retinoblastoma, hepatoblastoma, and germ cell, bone, and soft tissue tumors in children: a systematic review and meta-analysis.
Frontiers in oncology
73.0
16
Clinical outcomes in pediatric acute lymphoblastic leukemia: a retrospective cohort study from a tertiary center in Indonesia.
Frontiers in pediatrics
62.7
17
PROX1-associated lymphatic reprogramming signatures in pediatric adamantinomatous craniopharyngioma: a comparative study with adult cases.
Frontiers in pediatrics
57.5
18
Case Report: Delayed diagnosis of pancreatic solid pseudopapillary neoplasm in a boy initially misdiagnosed as traumatic retroperitoneal hematoma.
Frontiers in pediatrics
47.5
19
The complications of irradiation or busulfan for CAYA before hematopoietic stem cell transplantation: a systematic review and meta-analysis.
Frontiers in pediatrics
79.8
20
Analysis of factors influencing HPV vaccination willingness of parents of students in China based on the theory of planned behavior.
Frontiers in public health
59.0
21
When Does Infantile Nystagmus Predict Optic Pathway Glioma?
Pediatric neurology
67.4
22
Caregiver knowledge and Attitudes toward Human Papillomavirus Vaccination among adolescent girls living with HIV in Sierra Leone: A health facility-based cross-sectional study.
medRxiv : the preprint server for health sciences
61.0
23
Standalone NF1: guiding the transition from paediatric to adult care.
Drugs in context
58.0
24
Low-dose ionizing radiation exposure and tumor risk: An umbrella review of systematic reviews and meta-analyses.
Journal of hazardous materials
73.12
25
Recurrent Juvenile Nasopharyngeal Angiofibroma: Two Cases Emphasizing the Role of Follow-Up and Staging in Surgical Planning.
International medical case reports journal
58.4
26
Effect of HPV Vaccine Introduction at 9-10 years: A Randomized Clinical Trial.
medRxiv : the preprint server for health sciences
75.7
27
Exploring the Role of Immune Checkpoint Inhibitors in Retinoblastoma Prognosis.
Current pharmaceutical design
67.56
28
Invasive mechanical ventilation, functional decline at pediatric intensive care unit discharge, and post-discharge mortality in critically ill pediatric cancer patients: a retrospective cohort study.
Critical care science
68.0
29
Composite Hemangioendothelioma of the Right Atrium Presenting With Cardiac Tamponade in an Adolescent.
World journal for pediatric & congenital heart surgery
58.4
30
Palliative Care Support for Pediatric Cancer Patients Enrolled in Phase I Clinical Trials.
Journal of palliative medicine
78.8
31
Acute abdominal presentation of mantle cell lymphoma mimicking acute appendicitis: a case report.
Journal of surgical case reports
47.5
32
AGA Clinical Practice Update on Surveillance of Pancreatic Cystic Lesions and Hepatocellular Carcinoma in Older Adults: Expert Review.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
75.9