← Back to all signals
RESEARCH PAPER ANALYSIS

Factors influencing sense of coherence in caregivers of children with acute leukaemia.

AI interpretation is pending for this paper.

Open original publication →
PMID40448109
JournalBMC nursing
Publication Date2025-05-30
Ingested2026-08-02 12:04 AM
EXECUTIVE SUMMARY

What the AI sees

Not AI summarized yet.

WHY IT MATTERS

Research significance

Pending deeper interpretation.

ABSTRACT

Source abstract

BACKGROUND: As an important protective factor for caregivers' well-being, a sense of coherence can reduce a series of negative effects brought about by the care process. Previous studies have focused on the adverse factors that lead to psychological problems in caregivers of children with acute leukaemia. This study explored factors that promote the physical and mental health of caregivers, with a particular focus on the sense of coherence and its influencing factors among caregivers of children with acute leukaemia. METHODS: This study used a cross-sectional design and was completed between February and September 2023. We conducted a questionnaire survey using convenience sampling with 287 children with acute leukaemia and their caregivers who were admitted to a children's hospital in Jiangsu Province. Caregivers completed a general information questionnaire, Sense of Coherence Scale, Social Support Rating Scale, Simplified Coping Style Questionnaire, and General Self-Efficacy Scale. Data were analysed using independent sample t-tests, one-way analysis of variance, Pearson's correlation analysis, and multiple linear regression analysis using the SPSS software. RESULTS: Univariate analysis identified several influencing factors, including caregivers' gender, relationship with children, education level, current work status, family monthly income per capita, cumulative care time, medical payment method, clinical risk classification, self-care ability, and recurrence. Bivariate analysis showed that sense of coherence was positively correlated with social support, positive coping style, and self-efficacy. Multiple linear regression analysis showed that positive coping style, self-efficacy, family monthly income per capita, caregivers' gender, social support, self-care ability, and the caregiver's relationship with the child contributed to the model, collectively explaining 58.1% of the total variance. CONCLUSION: The overall sense of coherence among caregivers of children with acute leukaemia was notably low. According to the identified influencing factors, it is crucial to implement targeted interventions and support caregivers in fully utilising internal and external family resources to promote positive coping strategies and improve their sense of coherence. CLINICAL TRIAL NUMBER: Not applicable.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 [Evaluation of the Educational Effects of Cervical Cancer and HPV Vaccine Education for Junior High School Students]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 41.7 2 The National Couples' Health and Time Stress Biology Study (NCHAT-BIO): Wave 1 Methodology Report and Wave 3 Preview. Biopsychosocial science and medicine 65.7 3 Communication quality shapes the sustainability of pediatric early warning system. BMC health services research 63.4 4 Treatment of children with Kawasaki disease complicated by selective IgA deficiency using immunoglobulin preparations: a case report. BMC pediatrics 56.24 5 Hotspot mutations and tumour spectrum in von Hippel-Lindau syndrome: genotype-phenotype analysis of a large Chinese cohort. Journal of cancer research and clinical oncology 64.7 6 Perioperative outcomes and appendiceal malignancy in elderly patients with acute appendicitis: a comparative retrospective cohort study. Langenbeck's archives of surgery 68.0 7 Posttransplant lymphoproliferative disorders following hematopoietic stem cell transplantation: a clinicopathological study of a large single-center cohort. Annals of hematology 66.7 8 Therapeutic NAMPT inhibition reveals a targetable metabolic vulnerability in neuroblastoma. Journal of experimental & clinical cancer research : CR 60.04 9 Comparison of thyroglossal duct cysts in adults and children: 11 years of clinical experience. Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 67.8 10 Adult Pott's Puffy Tumor in the ED. Cureus 49.9 11 Long-term remission after surgical excision and minimal rituximab exposure in localized high-grade B-cell lymphoma with 11q aberration. Journal of clinical and experimental hematopathology : JCEH 62.56 12 Sixteen-year changes in hazardous metal(loid)s in urban topsoils: Land-use-specific enrichment and PM₁₀-based human health risk. Journal of hazardous materials 58.7 13 Mesenchymal Malignant Transformation in Metanephric Stromal Tumor: Expanding the Pathologic Spectrum of Metanephric Neoplasia. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 55.0 14 Intramuscular Myxoma of the Shoulder in Neurofibromatosis Type 1. Cancer diagnosis & prognosis 49.9 15 Hepatic Tumoral Calcinosis in a Patient With Obesity and Metabolic Syndrome: A Case Report. Case reports in surgery 47.5 16 A Large Multicenter Cohort of Ataxia-Telangiectasia: Clinical, Immunologic, Genetic, and Survival Outcomes. European journal of neurology 68.62 17 Effects of insulin resistance on pregnancy outcomes and complications in women with polycystic ovary syndrome. The Journal of international medical research 67.0 18 Genetic testing considerations for hereditary duodenopancreatic neuroendocrine tumors. Journal of neuroendocrinology 62.5 19 Clinical Features, Treatments, and Outcomes of an International Cohort of 96 Children with Takayasu Arteritis. ACR open rheumatology 67.74 20 It's a Trap! CDK8 Inhibition Reveals a Shared Vulnerability through Mediator Trapping in Fusion-Driven Pediatric Sarcomas. Cancer discovery 56.5 21 Recruitment, Retention, and Patient Engagement of Adolescents and Young Adult Cancer Survivors in Psycho-Oncology Research: A Qualitative Study. Journal of adolescent and young adult oncology 56.0 22 The Role of Genetic Profiling in Pediatric Brain Tumors. Balkan medical journal 47.5 23 Voices in Molecular Pharmaceutics: Meet Dr. Ritika Gupta Who Seeks to Light up Pediatric Tumors with Targeted Fluorescence Imaging Agents. Molecular pharmaceutics 47.5 24 Patterns of Pediatric Cancer Care at a Tertiary Center in Pakistan: A Hospital-Based Registry Analysis. Pediatric blood & cancer 66.9 25 Natural Killer Cell-Based Immunotherapy in Retinoblastoma: Biological Basis, Preclinical Evidence, and Translational Challenges. Pediatric blood & cancer 66.5 26 Perioperative Management of Children, Adolescents and Young Adults Undergoing Surgical Treatment for Oncologic Thoracic Disease: Retrospective Single-Center Analysis. Pediatric blood & cancer 67.14 27 A Clot Before the Cancer: Cerebral Venous Sinus Thrombosis as the Initial Presentation of Childhood Acute Leukemia-A Case Report and Literature Review. Pediatric blood & cancer 39.0 28 Creation of a Tailored Social Media Campaign to Educate Adolescents and Young Adults About Clinical Trials: The Talk to Me Study. Journal of adolescent and young adult oncology 72.2 29 Re: Robot-assisted minimally invasive surgery in paediatric neuroblastoma: does the actual technology truly expand selection criteria? Pediatric surgery international 47.5 30 Enablers and barriers to human papillomavirus vaccination implementation among key stakeholders in Ethiopia: A qualitative study. PloS one 62.5 31 Cohort Profile: The Adolescent and Young Adult Tracking Engagement and Management Skills (AYA TEAMS) longitudinal cohort of childhood cancer survivors in the United States. PloS one 67.4 32 Identifying novel genomic alterations in relapsed childhood B-ALL: a report from the Children's Oncology Group. Blood 84.42
PATIENT-FRIENDLY SUMMARY

Factors influencing sense of coherence in caregivers of children with acute leukaemia.

For education only—not personal medical advice.

Before you continue

AI-assisted research information

Neurocompute uses AI to summarize scientific papers, interpret research signals, and suggest relevant reference links. AI-generated content can be incomplete, misleading, or wrong, and generated links may be irrelevant or unavailable.

Our reviewed outputs have performed strongly to date, but past accuracy is not a guarantee. Verify summaries, scores, claims, and links against the original publication before relying on them.

This platform is for research and education only. It does not provide medical advice, diagnosis, treatment recommendations, or clinical guidance.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic