← Back to all signals
RESEARCH PAPER ANALYSIS

Management Approach of Vascular Anomalies of Head and Neck Region: A Clinical Study in Tertiary Care Center.

AI interpretation is pending for this paper.

Open original publication →
PMID40727142
JournalIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
Publication Date2025-06-09
Ingested2026-08-02 12:04 AM
EXECUTIVE SUMMARY

What the AI sees

Not AI summarized yet.

WHY IT MATTERS

Research significance

Pending deeper interpretation.

ABSTRACT

Source abstract

BACKGROUND: Vascular anomalies are broadly classified into vascular tumors and vascular malformations, as per the classification by the international society for the study of vascular anomalies (Kunimoto et al. Int J Mol Sci 23(1):388, 2022) (ISSVA). Vascular tumors arise due to abnormal endothelial proliferation, with infantile hemangiomas (IHs) being the most prevalent benign type, occurring in approximately 5-10% of infants (Wildgruber et al. Insights Imaging 10(1):30, 2019). These tumors demonstrate a predilection for the head and neck region and are more commonly observed in females (George et al. J Oral Maxillofac Pathol 18(Suppl 1):S117-S120, 2014). In contrast, vascular malformations represent congenital structural anomalies of blood or lymphatic vessels, resulting from errors in embryonic vascular development. METHODS: This prospective observational study was conducted over one year at a tertiary referral center, focusing on patients diagnosed with vascular Anomalies. The objective was to evaluate the clinical presentation, management strategies, and outcomes, with an emphasis on aligning treatment approaches with current literature and evidence-based protocols. RESULTS: A total of 45 patients were included in the study, comprising 24 males (53.33%) and 21 females (46.67%). The age of presentation ranged from infancy to 70 years. Two patients (4.44%) were infants (0-1 year), 10 patients (22.22%) were in the age group of (1-18 years), and the majority, 33 patients (73.33%), were adults (> 18 years). The most frequently involved anatomical sites were the face (46.67%) followed by the oral cavity and oropharynx (44.44%), with symptomatology varying according to lesion size, site, and extent. Surgical intervention was the most commonly employed treatment modality (44.44%), demonstrating favorable outcomes with low recurrence rates. Sclerotherapy was utilized in 35% of cases and was particularly effective for select lesion types. In the pediatric cohort, oral propranolol was administered with positive therapeutic response. Combined approaches, particularly surgery following embolization, yielded enhanced outcomes in complex or extensive lesions. CONCLUSION: Surgical management remains the cornerstone of treatment for vascular malformations, offering the most definitive results and lowest recurrence rates. In selected cases, adjunctive therapies such as preoperative embolization or sclerotherapy can optimize surgical outcomes. A multidisciplinary, individualized treatment approach based on lesion type, location, and patient age is essential for optimal management of vascular anomalies.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 Molecular diagnostics in paediatric oncology in Latin America: findings from the Latin America Regional Advisory Committee (RAC LATAM) regional assessment. Ecancermedicalscience 54.0 2 PEDCan: acceptability and feasibility of a mobile application to support primary health-care workers in recognising clinical features of childhood cancer in Uganda. Ecancermedicalscience 59.0 3 Li-Fraumeni Syndrome: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations. Cureus 82.5 4 Mechanism-Driven Evolution of Fertility-Sparing Treatment and Precision Management of Special Populations in Endometrial Cancer: A Review. Cancers 85.09 5 Exposure to Particulate Matter (PM) During Pregnancy and Non-Hodgkin Lymphomas in Children. Cancers 69.5 6 Whole-Body MRI Versus 18F-FDG-PET/CT for the Detection of Nodal and Distant Metastases in Pediatric Patients with Solid Tumors. Cancers 70.9 7 Prehabilitation Practices for Paediatric Haematopoietic Stem Cell Transplantation: A Survey and Patient and Public Involvement Study of Healthcare Professionals. Nutrients 62.2 8 Comparison of Radiological and Postoperative Tumor Volume Measurements for SIOP Risk Stratification in Wilms Tumord. Diagnostics (Basel, Switzerland) 59.9 9 Neurofilament Light Chain: A Potential Biomarker for Chemotherapy-Induced Peripheral Neuropathy in Pediatric and Adolescent Young Adults with Leukemia or Lymphoma. Cancers 73.59 10 Immune Modulation in Peripheral Blood of Cystic Fibrosis Patients Following Ex Vivo Co-Culture with Mesenchymal Stem Cells. Cells 61.2 11 The Gut-Brain Axis and Dietary Patterns in Shaping Long-Term Neurocognitive and Psychosocial Outcomes in Adolescent and Young Adult Survivors of Childhood Cancer: A Systematized Narrative Review. Nutrients 85.6 12 Association of Recorded Cerebrospinal Fluid Diversion with Registry Outcome Status in Pediatric Medulloblastoma: An Exploratory 10-Year Single-Centre Cohort Study. Journal of clinical medicine 66.1 13 Changes in Ultrasound-Based Risk Stratification and Surgical Selection of Adnexal Masses During the COVID-19 Pandemic: A Single-Center Retrospective Study. Diagnostics (Basel, Switzerland) 65.4 14 Multi-Target HCC Blood Test Demonstrates Consistent Performance Across Subgroups of Patients with Chronic Liver Disease. Cancers 67.0 15 Pediatric Mycosis Fungoides and Hydroa Vacciniforme Lymphoproliferative Disorder. Cancers 62.3 16 Silent Verb Generation During fMRI Reveals Post-Radiotherapy Alterations in Cerebellar-Cerebral Language Regions in Patients Treated for Medulloblastoma. Cancers 71.24 17 Evaluating the Prognostic Relevance of Pre-Treatment Epstein-Barr Virus Levels in Non-Endemic Pediatric Nasopharyngeal Carcinoma. Cancers 70.34 18 Severe Suprasystemic Refractory Pulmonary Hypertension in a Neonate with Stüve-Wiedemann Syndrome Associated with Biallelic LIFR Variants: Molecular Insights and a Neonatal Case Report. International journal of molecular sciences 51.12 19 Clinical Outcome and Prognostic Factors in Childhood Acute Lymphoblastic Leukemia-A Retrospective Cohort Study of Patients from Southern Mexico. Journal of clinical medicine 70.3 20 Case Report: Single-cell transcriptomic profiling of a pediatric ALK-negative gastric inflammatory myofibroblastic tumor. Frontiers in immunology 45.5 21 Case Report: Mixed gonadal dysgenesis with Müllerian remnants mimicking a prostatic utricle in a child with 45,X/46,XY/47,XYY mosaicism. Frontiers in pediatrics 49.0 22 Sodium fluorescein in pediatric brain tumor surgery: a retrospective volumetric analysis of resection extent and consistency. Frontiers in surgery 56.0 23 Electromagnetic Surgical Navigation for Accurate Pediatric Tumor Localization: A Preclinical Animal Cadaver Study. Cancers 59.6 24 T-lymphoblastic leukemia/lymphoma: a comprehensive review of pathology, molecular features, and differential diagnosis. Journal of pathology and translational medicine 64.0 25 Family Bonds at the End of Life: A Qualitative Study of Meaning Reconstruction Through Intergenerational Relationships Among Older Adults With Advanced Lung Cancer. Psycho-oncology 57.5 26 Scenario-Related Anxiety, Self-Reported Critical Incidents, and Burnout Among Anesthesia Professionals: A Cross-Sectional Survey. Healthcare (Basel, Switzerland) 59.0 27 Research Progress on Angiogenesis and Involution Mechanisms of Infantile Hemangioma and Its Regulation by Active Components of Salvia miltiorrhiza. International journal of molecular sciences 59.75 28 Nutritional Prevention of Oxidative Stress-Induced Cardiotoxicity in Pediatric Cardio-Oncology: Molecular Mechanisms and Translational Perspectives-A Narrative Review. International journal of molecular sciences 72.37 29 Perceived Facilitators and Barriers Inform Young Adult Cancer Survivors' Preferences for Physical Activity and Diet Interventions: A Qualitative Study. Nutrients 62.2 30 Three-Dimensional Left Ventricle Strain Echocardiography in the Detection of Anthracycline Cardiotoxicity in Children with Acute Lymphoblastic Leukemia-Retrospective Case-Control Analysis and Relation to the Cardiotoxicity Risk Factors Assessment. Cancers 70.22 31 Chemotherapy-Mediated Purging Before Testicular Organoid Generation Significantly Reduces Cancer Cells While Not Significantly Reducing Germ Cells. International journal of molecular sciences 63.34 32 Phenotype-Specific Pharmacogenetic Patterns of Methotrexate Neurotoxicity in Pediatric Acute Lymphoblastic Leukemia. Journal of clinical medicine 67.02
PATIENT-FRIENDLY SUMMARY

Management Approach of Vascular Anomalies of Head and Neck Region: A Clinical Study in Tertiary Care Center.

For education only—not personal medical advice.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic