← Back to all signals
RESEARCH PAPER ANALYSIS

Deep learning model for early acute lymphoblastic leukemia detection using microscopic images.

AI interpretation is pending for this paper.

Open original publication →
PMID40783578
JournalScientific reports
Publication Date2025-08-09
Ingested2026-08-02 12:05 AM
EXECUTIVE SUMMARY

What the AI sees

Not AI summarized yet.

WHY IT MATTERS

Research significance

Pending deeper interpretation.

ABSTRACT

Source abstract

Cancer of bone marrow is classified as Acute Lymphoblastic Leukemia (ALL), an abnormal growth of lymphoid progenitor cells. It affects both children and adults and is the most predominant form of infantile cancer. Currently, there has been significant growth in the identification and therapy of acute lymphoblastic leukemia. Therefore, a method is required that is capable to accurately assessing risk by an appropriate treatment strategy that takes into account all relevant clinical, morphological, cytogenetic, and molecular aspects. However, to enhance survival and quality of life for those afflicted by this aggressive haematological malignancy, more research and clinical trials are required to address the issues associated with resistance, relapse, and long-term toxicity. Consequently, a deep optimized Convolutional Neural Network (CNN) has been proposed for the early diagnosis and detection of ALL. The design of the deep optimized CNN model consisted of five convolutional blocks with thirteen convolutional layers and five max pool layers. The proposed deep optimized CNN model is tuned using the hyperparameters such as 30 epochs, batch size 32 and optimizers, namely Adam and Adamax. Out of the two optimizers, the proposed deep optimized CNN model has outperformed using Adam optimizer with the points of accuracy and precision as 0.96 and 0.95, respectively.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 Isolated Plexiform Neurofibroma at the Liver Hilum in a Pediatric Patient: A Case Report. Cureus 47.5 2 Recurrent myxopapillary ependymoma: A diagnostic challenge. The Malaysian journal of pathology 53.1 3 Cross-cancer transcriptomic analysis reveals conserved developmental, ferroptosis, and immune remodeling modules in Wilms tumor and oral cancer. Frontiers in genetics 53.6 4 Biomineralized SERS Nanotags Encode Biomolecular Identity into Machine Learning-Resolvable Fingerprints. ACS applied materials & interfaces 56.0 5 Ewing sarcoma of the mandible in a child-reconstruction using a chondrocostal graft. Journal of surgical case reports 58.4 6 How adolescent and young adult cancer is portrayed in movies: reflections for supportive care. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 61.6 7 Synovial Sarcoma of the Hyoid Bone Treated With Trimodality Therapy. The Permanente journal 64.84 8 No genome-wide correlations and little shared genetic architecture between reproductive life-history traits and estrogen receptor-positive breast cancer risk. Molecular biology and evolution 57.5 9 Provider and Parent Perspectives on Prioritizing the "Asking and Monitoring" Pediatric Cancer Psychosocial Standards of Care. Pediatric blood & cancer 57.2 10 Assessing the Impact of Rituximab on Treatment Outcomes in Pediatric Advanced Mature B-Non Hodgkin Lymphoma - Authors' Reply. Indian journal of pediatrics 50.74 11 Non-invasive differentiation of diffuse midline glioma and midline glioblastoma using DCE-MRI perfusion parameters and machine learning classification in pediatric and young adult patients. Neuroradiology 72.0 12 Closing the research-to-practice gap: Using a plan-do-study-act approach to test innovative interventions to increase HPV immunization uptake in Canada. Canadian journal of public health = Revue canadienne de sante publique 58.7 13 PTPN11 variants in four Chinese patients: a case series and genotype-phenotype analysis. European journal of dermatology : EJD 53.0 14 Understanding retention in longitudinal surveys conducted by mobile phone in lower-resource contexts: A case study from Kenya. PloS one 37.0 15 Prevalence of High Tumor Mutational Burden Among Pediatric Patients With Solid Tumors. Pediatric hematology and oncology 72.4 16 Increased prevalence of Helicobacter pylori and CagA seropositivity in Bulgarian children with type 1 diabetes mellitus. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 61.0 17 Delayed Appendectomy in Pediatric Cancer Patients with Leukopenia is Associated with Worsened Outcomes. Journal of pediatric surgery 57.5 18 Methotrexate induces alterations in one-carbon metabolism and in plasmalogen and phosphatidylcholine levels in CSF of juvenile rats. Brain research bulletin 60.7 19 Exploring the process of social support among parents of children with cancer in the sociocultural context of Iran: a grounded theory study protocol. BMJ open 58.4 20 Adaptation and feasibility of a group intervention for parents after the loss of a co-parent to cancer: a mixed-methods study protocol. BMJ open 75.7 21 Explainable Radiomics Model Based on Intratumoral and Peritumoral CEMRI Features: Predicting Macrotrabecular-Massive Hepatocellular Carcinoma and Evaluating Immune Status. Academic radiology 73.4 22 Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study. Cancer medicine 72.04 23 Giant and atypical eccrine tumors of the eyelid: A clinicopathologic analysis. Indian journal of ophthalmology 55.0 24 Development of the Novel FLOX Score to Assess Risk of Intubation in Children With Immunocompromising Conditions Receiving High Flow Nasal Cannula. Pediatric pulmonology 64.0 25 Value of high-frequency color Doppler ultrasound for preorbital mass diagnosis. Indian journal of ophthalmology 62.5 26 Hip arthroplasty following proximal femoral tumour resection in children : the impact of age and articulation on implant survival and the outcomes following acetabular revision. The bone & joint journal 62.12 27 Patient-specific 3D-printed Anatomical Models for Intraoperative Osteotomy Verification in Joint-sparing Surgery for Osteosarcoma: A Report of Two Cases. Anticancer research 53.1 28 Mesenteric Lymphangioma Complicated by Small-Bowel Volvulus in a Child: A Case Report and Review of the Literature. The Tokai journal of experimental and clinical medicine 51.9 29 Successful Engraftment Following Second Cord Blood Transplantation After Graft Failure in a Child With Relapsed B-ALL. The Tokai journal of experimental and clinical medicine 62.42 30 Pediatric Acute Leukemias: Epidemiological, Clinical Features, and Diagnostic Contribution of Flow Cytometry in a Resource-Limited Setting. Cureus 61.5 31 Patient Care of Pregnant Women With Chronic Myeloid Leukemia in a Resource Limited Setting-Case Reports From Ghana. Case reports in hematology 63.8 32 Porto-sinusoidal vascular disorder and sinusoidal obstructive syndrome in patients treated with thiopurines: a systematic review. Annals of hepatology 75.1
PATIENT-FRIENDLY SUMMARY

Deep learning model for early acute lymphoblastic leukemia detection using microscopic images.

For education only—not personal medical advice.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic