← Back to all signals
RESEARCH PAPER ANALYSIS

Influence of psychosocial adaptation on existential distress among young breast cancer survivors in the rehabilitation period: An analysis of the chain mediating effects of social support and psychological resilience.

In a cross-sectional survey of 390 Chinese breast cancer survivors aged 18–49 within five years after treatment, poorer psychosocial adaptation was associated with greater existential distress, with statistical mediation through perceived social support and psychological resilience.

Open original publication →
PMID42579654
JournalPloS one
Publication Date2026-08-11
Ingested2026-08-17 12:23 AM
EXECUTIVE SUMMARY

What the AI sees

In a cross-sectional survey of 390 Chinese breast cancer survivors aged 18–49 within five years after treatment, poorer psychosocial adaptation was associated with greater existential distress, with statistical mediation through perceived social support and psychological resilience.

WHY IT MATTERS

Research significance

The study provides associative evidence that social support and resilience are linked to lower existential distress; it suggests—but does not demonstrate—that interventions strengthening these factors could improve psychological outcomes during breast cancer rehabilitation.

ABSTRACT

Source abstract

This study investigated the influence of psychosocial adaptation on existential distress among young breast cancer survivors during the rehabilitation period, with a focus on the chain-mediating roles of social support and psychological resilience. A cross-sectional survey was conducted with 390 young Chinese breast cancer survivors (aged 18-49 years, within 5 years post-treatment) recruited from tertiary hospitals. Participants completed standardized measures assessing psychosocial adaptation (PAIS-SR), social support (PSSS), psychological resilience (CD-RISC10), and existential distress (DS-II). Results from correlation analysis revealed that poorer psychosocial adaptation was significantly associated with higher existential distress (r = 0.510), lower social support (r = -0.306), and reduced psychological resilience (r = -0.412). Structural equation modeling demonstrated a significant direct effect of psychosocial adaptation on existential distress (effect = 0.514). Crucially, mediation analysis using bootstrapping confirmed three significant indirect pathways: the independent mediation of social support (effect = 0.061, 51.3%), the independent mediation of psychological resilience (effect = 0.040, 33.6%), and their sequential chain mediation (effect = 0.018,15.1%). The findings indicate that social support and psychological resilience function as both independent and sequential protective factors, mitigating the impact of psychosocial adaptation challenges on existential distress. The study underscores the importance of integrated interventions that enhance external support systems and foster internal resilience to improve psychological outcomes for young breast cancer survivors navigating the unique challenges of the rehabilitation phase.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 From Childhood Ingestion to Adult Obstruction: A Long-Retained Synthetic Gastric Foreign Body. Cureus 59.5 2 Deep learning-based detection of pediatric brain tumor presence on MRI. Neuro-oncology advances 58.4 3 Efficacy and safety of Heshu Xiaoji pills combined with standard treatment strategy in hepatitis B virus-related hepatocellular carcinoma: a single-center, open-label, prospective controlled, real-world cohort study. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 69.04 4 Bioelectrical impedance parameters and nutritional status of pediatric patients with hematological malignancies: a cross-sectional study. Nutricion hospitalaria 65.8 5 Single-cell analysis and EpCAM-based microfluidic chip detection of PD-L1 on circulating tumor cells for prognostic prediction in epithelial ovarian cancer. Frontiers in oncology 55.2 6 Navigating CAR-T translation in Australia: lessons from an academic program. Frontiers in medicine 71.9 7 Pediatric hyperuricemia: genetic basis, metabolic mechanisms, and clinical implications. Frontiers in endocrinology 63.25 8 Weighted epigenetic site correlation network analysis of chemotherapy impacts on osteosarcoma cancer survivors' male fertility, sperm, and endocrine parameters. Environmental epigenetics 62.94 9 Acute Sector Cancer Physiotherapy Service Provision and Workforce. Irish medical journal 63.14 10 Influencing Factors Associated With Infantile Hemangioma: A Case-Control Study Among Chinese Pediatric Populations. The Journal of dermatology 71.4 11 ODC1 inhibition and neuroblastoma: A drug-target Mendelian randomization, eQTL colocalization and drug sensitivity study. British journal of clinical pharmacology 66.76 12 Intraosseous calvarial haematoma mimicking a skull tumour in a child with Noonan syndrome: a case report. Journal of surgical case reports 45.5 13 Head and Neck Rhabdomyosarcoma in Children: An Otolaryngological Perspective on Diagnostic and Therapeutic Approaches. Current oncology reports 73.54 14 Pilomatricoma in an Octogenarian: A Case Report of an Exceptional Late-Life Presentation. The American journal of case reports 47.5 15 Blinatumomab-induced catastrophic immune effector cell-associated neurotoxicity with diffuse cerebral edema in a patient with ALL: Case report. International journal of clinical pharmacology and therapeutics 67.0 16 Impact of Intensified Chemoimmunotherapy Regimens in Aggressive Non-Hodgkin Lymphoma on Reproduction Patterns. European journal of haematology 66.92 17 Demographics, risk factor profiles and etiologies in young ischemic and hemorrhagic stroke - the United Kingdom Young Stroke Study (UKYSS). Journal of neurology 59.1 18 Surgical management of quadrigeminal arachnoid cysts in children: A single-center study of 15 cases according to the Cinalli classification. Neurosurgical review 61.8 19 Recurrent Cardiac Arrest in a Pediatric Patient with Hypertrophic Cardiomyopathy and a Myocardial Bridge: Player or Spectator? Pediatric cardiology 49.9 20 Subperineural 'onion-peeling' dissection for maximizing extent of resection and facial nerve preservation for onco-functional balance in vestibular schwannoma surgery. Journal of neuro-oncology 67.0 21 Is vitreoretinal traction the cause of 'Combined Hamartoma of the Retina and Retinal Pigment Epithelium' (CHRRPE)? A case series and proposal for 'Traction-Induced Retinal and Retinal Pigment Epithelium Lesion' (TRIPEL). Retina (Philadelphia, Pa.) 54.0 22 1Unilateral Le Fort I Advancement Versus Dentoalveolar Transport Distraction in Patients With Large Alveolar Clefts: Protocol for a Prospective Observational Study. JMIR research protocols 60.9 23 Epidemiology and long-term survival of primary central nervous system germ cell tumors in Korea: a nationwide population-based study, 2005-2022. Neuroepidemiology 59.12 24 Frequency and prognostic outcomes of emergency diagnosis in 13 non-neoplastic conditions in England: A population-based cohort study using linked electronic health records of 1.7 million patients. PLoS medicine 65.5 25 Burden of early-onset pancreatic cancer and its association with risk factors in women of childbearing age. PloS one 65.0 26 Circulating CTRP-1 levels are elevated in women with polycystic ovary syndrome: A case-control study. PloS one 64.0 27 Predictive Risk Model for Early Post-Treatment Acute Care Use in Adolescent and Young Adult Patients With Cancer. JCO oncology practice 69.74 28 Cryoablation of Malignancies and Aggressive Benign Diseases in Children: Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel. Journal of vascular and interventional radiology : JVIR 64.7 29 On-demand transarterial chemoembolisation combined with atezolizumab and bevacizumab in patients with untreated hepatocellular carcinoma (TALENTACE): a multicentre, randomised, open-label, phase 3 trial. The lancet. Gastroenterology & hepatology 84.4 30 Methylation profile scores in child and adolescent health: a practical guide. The Lancet. Child & adolescent health 61.1 31 Somatic mutations in human ontogenesis and their impact on health. Ageing research reviews 40.0 32 MicroRNA profiles as diagnostic tools in pediatric acute lymphoblastic leukemia. Clinica chimica acta; international journal of clinical chemistry 63.0
PATIENT-FRIENDLY SUMMARY

Influence of psychosocial adaptation on existential distress among young breast cancer survivors in the rehabilitation period: An analysis of the chain mediating effects of social support and psychological resilience.

For education only—not personal medical advice.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic