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RESEARCH PAPER ANALYSIS

Development of an intervention for middle adolescents (15-17 years old) using the Behaviour Change Wheel (BCW) to empower adolescent decision-making regarding HPV vaccination uptake.

Using a systematic review and Northern Ireland stakeholder interviews and focus groups structured by the Behaviour Change Wheel and COM-B model, the study developed a school-based HPV education intervention for adolescents aged 15–17 that includes a vaccination opportunity and supporting public media campaign.

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PMID42599892
JournalPloS one
Publication Date2026-08-14
Ingested2026-08-17 12:23 AM
EXECUTIVE SUMMARY

What the AI sees

Using a systematic review and Northern Ireland stakeholder interviews and focus groups structured by the Behaviour Change Wheel and COM-B model, the study developed a school-based HPV education intervention for adolescents aged 15–17 that includes a vaccination opportunity and supporting public media campaign.

WHY IT MATTERS

Research significance

The record supports a theory-informed intervention addressing identified behavioral and system barriers; it is reasonable to infer—but not yet demonstrated—that adolescent-focused education, decision-making support, and convenient vaccination access could increase HPV vaccine uptake and thereby contribute to long-term prevention of HPV-associated cancers.

ABSTRACT

Source abstract

INTRODUCTION: In the United Kingdom, where a school-based human papillomavirus vaccination programme vaccinates 12-13 year old students, parents/guardians have been the primary decision-makers regarding receipt of the vaccination. As the average age of first sexual intercourse is 15-17 years old, education at this time could provide an opportunity for unvaccinated students to self-consent to vaccination. The aim of this study was to develop a HPV intervention, aimed at middle adolescents (15-17 years old), using the 3 stages of the Behaviour Change Wheel. METHODS: A systematic review informed target behaviours and populations. Focus groups and interviews were conducted throughout Northern Ireland with immunisation nurses (n = 26), middle adolescents (n = 34), and post-primary school teachers (n = 12) and nurses (n = 6). Data analysis was guided by the COM-B model to inform a Behavioural Diagnosis. Subsequently, appropriate intervention functions, policy categories and Behaviour Change Techniques were selected with consideration of APEASE criteria. RESULTS: The systematic review highlighted the lack of interventions designed for middle adolescents; existing interventions were sparse, commonly not based on behavioural theory and focused on female cancers. The study identified twelve barriers to three target behaviours which included: empowering students to make decisions about HPV; empowering professionals' to design and deliver the intervention; and increasing positive public attitudes regarding HPV vaccination. A behaviour change HPV intervention was developed which included school-based HPV education aligned with mandated curriculum changes, alongside vaccination opportunity. The study identified content, mode of delivery and desirable qualities/characteristics of a professional who could design/deliver the HPV education. A public media campaign was deemed important in supporting this central education. DISCUSSION AND CONCLUSION: This study highlights political, social and cultural barriers to HPV intervention success and the need for Public Health Authority and Education Authority support. A feasibility pilot study should be undertaken to assess the real-world practicality of this HPV intervention.

SUPPORTING PAPER SET

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International medical case reports journal 47.5 12 Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 84.86 13 Premature treatment cessation in pediatric acute myeloid leukemia due to excessive toxicity: clinical experiences and patient outcomes - a case series. Pediatric hematology and oncology 65.06 14 Rare presentation of hydrocephalus occlusus caused by membranous obstruction of the foramina of Magendie and Luschka: a case report. Journal of surgical case reports 47.9 15 Impact of 131I-MIBG dose escalation (12 vs. 18 mCi/kg) during conditioning for autologous hematopoietic stem cell transplantation in pediatric neuroblastoma: a retrospective cohort study. European journal of pediatrics 74.42 16 Invisible Enemy: CMV Retinitis Despite Persistent Blood PCR Negativity in Pediatric AML. Turkish journal of haematology : official journal of Turkish Society of Haematology 47.5 17 A real-world multi-institution experience of standard versus alternative dosing regimens of inotuzumab ozogamicin for relapsed/refractory paediatric B-cell acute lymphoblastic leukaemia. British journal of haematology 68.04 18 Adolescent Chronic Sleep Restriction Induces a Mesolimbic Hypodopaminergic State Associated with Addiction Vulnerability. Sleep 49.7 19 Incidence of intra-axial brain metastases in Eastern Finland. Journal of neuro-oncology 69.0 20 Ciliated hepatic foregut cyst in children and adolescents: a systematic review of clinical presentation, diagnosis, management, and outcomes. Pediatric surgery international 70.0 21 Adolescent M-CSF Administration Provides Durable Protection Against Trauma-Induced PTSD-Like Phenotypes in Male Mice Through Microglia-Dependent Mechanisms. Neurochemical research 57.75 22 Multimodal Combination Treatment in a Patient-Centered Approach is Associated with Improved Outcome in Relapsed/Refractory Sarcomas in Children: A Comparative Single-Institution Real-World Analysis. Oncology and therapy 68.18 23 Familial 46,XX Ovotesticular Differences in Sex Development Associated With an NR5A1 p.Arg92Trp Variant. Hormone research in paediatrics 38.5 24 Protective effect of folic acid supplementation on the proportion of micronucleated erythrocytes in Balb-C mice irradiated with computed tomography. International journal of radiation biology 48.5 25 Educating Pediatric Oncology Clinicians on Sexual Health Care for Adolescents and Young Adults With Cancer: Results From a Proof-of-Concept Study. JCO oncology practice 58.0 26 Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease. Hepatology communications 63.5 27 Dynamic Proton arc therapy for paediatric parameningeal rhabdomyosarcoma. Journal of applied clinical medical physics 67.54 28 Late-onset hypothalamic-pituitary dysfunction in a childhood cancer survivor treated with cranial irradiation. JCEM case reports 62.8 29 Late cardiopulmonary morbidity in patients with Hodgkin lymphoma: a retrospective nationwide registry study. Annals of hematology 66.6 30 Endoscopic techniques for removal of intraorbital foreign bodies - a clinical series. Acta neurochirurgica 60.9 31 Existing 'In-Between': A Qualitative Exploration of Individual, Interpersonal and Structural Influences on Empowerment Among Young Adults With Chronic Health Conditions. Health expectations : an international journal of public participation in health care and health policy 57.5 32 Transcriptome Analysis Identifies a Myeloid-Like Signature in Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia Patients With Poor Response to CD19 Chimeric Antigen Receptor T Cell Therapy. Cancer medicine 83.78
PATIENT-FRIENDLY SUMMARY

Development of an intervention for middle adolescents (15-17 years old) using the Behaviour Change Wheel (BCW) to empower adolescent decision-making regarding HPV vaccination uptake.

For education only—not personal medical advice.

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