Breast disorders in adolescence: Etiological, clinical, and therapeutic aspects.
This retrospective case series of 127 adolescents found that fibroadenomas predominated among females and pubertal gynecomastia among males, with some secondary gynecomastia linked to hypogonadism or medication use and 40 patients undergoing surgery.
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This retrospective case series of 127 adolescents found that fibroadenomas predominated among females and pubertal gynecomastia among males, with some secondary gynecomastia linked to hypogonadism or medication use and 40 patients undergoing surgery.
Research significance
The study provides descriptive evidence that comprehensive evaluation can identify potentially addressable secondary causes of adolescent gynecomastia; it is reasonable to infer that cause-directed management might avoid or better select surgical treatment, but comparative effectiveness, safety, and oncology-specific benefit were not tested.
Source abstract
Introduction. Breast diseases in adolescents are rare and generally benign, although their treatment can be complex. Objective. To describe the etiology, clinical presentation, and therapeutic management of adolescents with breast conditions at a tertiary care hospital. Population and methods. Retrospective case series study. The study included patients aged 10 to 18 years with suspected breast pathology who were treated between 2020 and 2024. Clinical and treatment data, as well as information on comorbidities, were collected. Results. A total of 127 patients were analyzed (median age: 16 years); 80 were female. In females, benign tumors predominated, primarily fibroadenomas, and 29 required surgery. In males, pubertal gynecomastia was the most common finding (n = 33), and secondary cases associated with hypogonadism or medication use were identified; 11 required surgery. Conclusion. Fibroadenomas were most common in girls, and gynecomastia in boys. The identification of secondary causes underscores the need for a comprehensive evaluation and targeted treatment.