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RESEARCH PAPER ANALYSIS

The global perspective on the evolution of nurse-related research in primary malignant bone tumors from 2004 to 2025: A bibliometric mapping and visual analysis study.

This bibliometric study mapped 686 publications on nursing research in primary malignant bone tumors from 2004 to 2025 and identified prognostic evaluation, clinical intervention, and subtype-targeted nursing care as emerging research themes.

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PMID42675752
JournalMedicine
Publication Date2026-08-28
Ingested2026-09-03 09:15 AM
EXECUTIVE SUMMARY

What the AI sees

This bibliometric study mapped 686 publications on nursing research in primary malignant bone tumors from 2004 to 2025 and identified prognostic evaluation, clinical intervention, and subtype-targeted nursing care as emerging research themes.

WHY IT MATTERS

Research significance

The evidence only identifies patterns and emerging topics in the literature; it indirectly suggests that prioritizing research on targeted nursing interventions could eventually improve supportive care or quality of life, but no intervention, therapeutic mechanism, or patient outcome was tested.

ABSTRACT

Source abstract

BACKGROUND: Primary malignant bone tumors, as diseases that mostly occur in adolescence, seriously affect all aspects of the lives of patients and their families. Effective bone tumor nursing is essential to maintain or improve patients' quality of life. Consequently, investigating bone tumor nursing is of utmost importance. This study aimed to provide a comprehensive, up-to-date synthesis of all published bone tumor nursing research articles and predict future areas of research and emerging trends. METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection to identify and analyze nursing research publications on primary malignant bone tumors from January 1, 2004, to September 12, 2025. The analysis and visualization were performed using various scientometric tools. Key characteristics of the publications, including country of origin, institutions, authors, journals, keywords, and references, were thoroughly examined. RESULTS: A total of 686 studies were included in the analysis, with 5376 authors, 70 countries, and 1422 institutions publishing research focused on nurse-related studies in primary malignant bone tumors. The United States and Memorial Sloan Kettering Cancer Center led the lists of publications. The most prolific cited and co-cited authors were Oeffinger, Kevin C, and Bacci, G, respectively. Pediatric Blood & Cancer published the most articles, whereas Journal of Clinical Oncology was the most frequently cited journal. The analysis of keyword co-occurrence and literature co-citation identified several emerging hotspots and trends in the field of primary malignant bone tumor nursing, including prognostic evaluation, clinical intervention, and subtype-targeted nursing care. CONCLUSION: In recent years, the advancement in nurse-related research in primary malignant bone tumors has accelerated rapidly. A comprehensive bibliometric analysis was utilized to verify the prominent areas of investigation and anticipate future research directions, with the aim of providing valuable insights and recommendations for future studies.

SUPPORTING PAPER SET

32 more papers to review

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1 The Tumour-Suppressive Role of miRNA-Loaded MSC-Derived Extracellular Vesicles in Osteosarcoma: A Systematic Review and Meta-Analysis. TheScientificWorldJournal 83.0 2 Tuberculosis of the Sphenoid Sinus Causing Blindness in a Pediatric Patient: A Case Report. Cureus 53.5 3 Recurrent Pleural Effusion as the Initial Presentation of T-lineage Lymphoblastic Malignancy in a Child: A Diagnostic Challenge. Cureus 58.4 4 Peripheral Precocious Puberty as the Initial Manifestation of Juvenile Granulosa Cell Tumor in Early Childhood. Cureus 61.4 5 Adenosylhomocysteinase drives epigenetic and metabolic reprogramming in ZFTA-RELA ependymoma. bioRxiv : the preprint server for biology 50.0 6 CBFA2T3-GLIS2 establishes transcriptionally permissive enhancer hypermethylation associated with venetoclax response in pediatric AML. bioRxiv : the preprint server for biology 54.72 7 A pediatric high-grade B-cell lymphoma with a rare complex cytogenetic profile: A case report. Tumori 51.5 8 Sunscreen use at Danish beaches in 2025 and long-term changes in sun protection related to public advice. Scandinavian journal of public health 56.0 9 Nationwide practice patterns and local recurrence after surgery for benign bone tumours: a retrospective study using the Bone and Soft Tissue Tumor Registry in Japan. International orthopaedics 61.9 10 Paraganglioma and childhood-onset optic atrophy in a SDHA compound heterozygous patient: an example of dual dominant and recessive inheritance. Mitochondrion 54.0 11 [Application and short-term efficacy of Da Vinci Xi robot-assisted transabdominal division of the rectourethralis muscle in ultra-low anastomosis surgery for low rectal cancer]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 64.9 12 Prenatal maternal inflammation and cognitive performance in offspring during late midlife. Brain, behavior, & immunity - health 57.5 13 Multi-tissue accumulation of potentially toxic elements and age-stratified non-carcinogenic dietary risk in fish from the Anzali Wetland, Caspian Basin. Toxicology reports 58.7 14 A novel spliceosome inhibitor triggers anti-tumor CD4+ and CD8+ T cell responses in murine models of pediatric-relevant cancer. Molecular therapy. Oncology 62.28 15 Prevalence and Associations for Use of Complementary and Alternative Medicine (CAM) Among Paediatric Cancer Patients in Norway: A Cross-Sectional Survey. Integrative cancer therapies 69.0 16 Portal cavernoma: epidemiological, clinical, etiological and outcome profiles - a 15-year retrospective study in a University Hospital in Rabat, Morocco. The Pan African medical journal 63.5 17 Artificial intelligence in Vietnamese healthcare: public awareness, demand, and willingness to pay. BMC health services research 60.2 18 Xp11.2 Translocation Renal Cell Carcinoma in an Elderly Woman: A Diagnostic Challenge - A Case Report. Case reports in oncology 49.0 19 The unbalanced needs and perceived supply of supportive care in family caregivers of patients with multiple myeloma: a cross-sectional study. BMC palliative care 59.9 20 Development and Optimization of 111 In-Dinutuximab-IRDye800, a Dual-Modality Intraoperative Molecular Imaging Agent for Pediatric Neuroblastoma Resection. bioRxiv : the preprint server for biology 77.4 21 High-Resolution Subtyping of Pediatric Low-Grade Glioma Using an Integrated Meta-Clustering Framework. bioRxiv : the preprint server for biology 67.5 22 Concordance of rapid whole genome and targeted long read sequencing of pediatric brain tumors with standard clinical testing. Research square 61.9 23 Synergistic targeting of EP300/CBP and EYA co-activators collapses the rhabdomyosarcoma core regulatory circuit. bioRxiv : the preprint server for biology 57.6 24 Clinical Presentation of, Treatment Approaches for, and the Impact of Social Determinants of Health on Pediatric Catatonia: A Structured Qualitative Synthesis and Targeted Literature Review. Cureus 66.04 25 Sequential Philadelphia-Positive Pre-B Acute Lymphoblastic Leukemia and Chronic Myeloid Leukemia With Distinct BCR::ABL1 Fusion Transcripts. Cancer reports (Hoboken, N.J.) 67.1 26 Intracranial germ cell tumours presenting with AVP deficiency and evolving panhypopituitarism: diagnostic pitfalls in early imaging and biopsy. Endocrinology, diabetes & metabolism case reports 64.0 27 A Subset of FOXO1-Fusion Negative Rhabdomyosarcoma With Round Cell (Alveolar) and "Burkitt-Like" Morphology Is Associated With High Amplification of MYCL: A Report From the Children's Oncology Group. Genes, chromosomes & cancer 57.5 28 Pediatric lynch-associated melanoma arising in ovarian teratoma: a case report. Gynecologic oncology reports 55.1 29 Case Report: Case series: growth hormone replacement for severe growth hormone deficiency during BRAF inhibitor therapy in pediatric low-grade glioma: long-term follow-up. Frontiers in endocrinology 70.3 30 Prognostic value of lymph node ratio in children with wilms tumor: a systematic review and meta-analysis. Frontiers in oncology 79.6 31 Real-world efficacy and safety of efgartigimod in patients with autoimmune encephalitis: a single-center retrospective analysiss. Frontiers in immunology 69.1 32 Combined aromatherapy and music or sound for emotional distress: a systematic review of controlled studies published between 2019 and 2026. Frontiers in psychology 84.84
PATIENT-FRIENDLY SUMMARY

The global perspective on the evolution of nurse-related research in primary malignant bone tumors from 2004 to 2025: A bibliometric mapping and visual analysis study.

For education only—not personal medical advice.

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