Management of Hemangiomas.
This management overview reports that most infantile hemangiomas involute without treatment, while complicated lesions are treated first-line with oral propranolol and surgery is generally reserved for cases unresponsive to medical therapy.
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This management overview reports that most infantile hemangiomas involute without treatment, while complicated lesions are treated first-line with oral propranolol and surgery is generally reserved for cases unresponsive to medical therapy.
Research significance
The supplied record presents propranolol as an established treatment for complicated infantile hemangioma; it does not test a new therapeutic hypothesis, although it implies that treatment stratification by complication status and medical response may guide escalation to surgery.
Source abstract
Infantile hemangioma (IH) is the most common benign soft tissue tumor of infancy with its pathogenesis yet to be elucidated. IHs are defined as vascular tumors of infancy and the diagnosis of IH is largely based on clinical findings, most commonly the characteristic strawberry appearance. IHs follow a stereotyped life cycle of rapid growth, a plateau, and eventual involution, and most do not require treatment. If complicated, first-line medical treatment of IH is oral propranolol, currently the most commonly used and efficacious drug. Surgery remains an option but is reserved for IHs primarily not responsive to medical treatment.