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RESEARCH PAPER ANALYSIS

Not Too Young to Understand: Meaning Making From the Perspectives of School-Aged Children With Cancer-A Scoping Review.

This scoping review of 39 studies synthesizes direct reports from children aged 6–12 with cancer and characterizes meaning making as a dynamic, developmentally grounded, relational, and socioculturally influenced process.

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PMID42684070
JournalPsycho-oncology
Publication Date2026-09-01
Ingested2026-09-04 09:15 AM
EXECUTIVE SUMMARY

What the AI sees

This scoping review of 39 studies synthesizes direct reports from children aged 6–12 with cancer and characterizes meaning making as a dynamic, developmentally grounded, relational, and socioculturally influenced process.

WHY IT MATTERS

Research significance

The review supports the observation that children actively make meaning during cancer; it is reasonable but untested to hypothesize that developmentally and culturally responsive psychosocial, communication, or palliative-care interventions targeting this process could improve coping, participation, or psychosocial-spiritual well-being.

ABSTRACT

Source abstract

BACKGROUND: Meaning making is increasingly recognized as an important determinant of psychosocial adjustment in adult oncology. However, how school-aged children make meaning of cancer and how developmental, relational, and sociocultural influences shape this process remain insufficiently characterized, particularly because frameworks are largely derived from adult research and centered on intrapersonal processes. AIMS: To synthesize evidence on meaning making among school-aged children with cancer and examine these findings through Park's meaning-making model while identifying dimensions not fully captured by the model. METHODS: A scoping review was conducted according to PRISMA-ScR guidelines. Four databases and reference lists were searched for peer-reviewed studies examining meaning making through direct reports from children aged 6-12 years with cancer. Park's meaning-making model informed study selection, data extraction, and deductive coding, while inductive coding identified dimensions not represented in the model. RESULTS: Thirty-nine studies were included. Children's meaning making encompassed global beliefs and developmental and healthcare-related goals; appraisals of threats to the self, normalcy, relationships, and future; and cognitive, emotional, socially informed, spiritual, experiential, and avoidance-related processes. Meaning making emerged as a dynamic, developmentally grounded, and relational process shaped by caregivers, healthcare professionals, and sociocultural contexts across the cancer trajectory. Evidence regarding children's sense of meaning or purpose and meanings made was limited. CONCLUSIONS: School-aged children actively construct meaning throughout the cancer trajectory. Integrating interdisciplinary support for meaning making that is child-centered and developmentally and culturally responsive into psychosocial care, serious illness communication, and pediatric palliative care may strengthen children's participation, coping, and psychosocial-spiritual well-being.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 Prevalence and Associations for Use of Complementary and Alternative Medicine (CAM) Among Paediatric Cancer Patients in Norway: A Cross-Sectional Survey. Integrative cancer therapies 69.0 2 Portal cavernoma: epidemiological, clinical, etiological and outcome profiles - a 15-year retrospective study in a University Hospital in Rabat, Morocco. The Pan African medical journal 63.5 3 Artificial intelligence in Vietnamese healthcare: public awareness, demand, and willingness to pay. BMC health services research 60.2 4 Xp11.2 Translocation Renal Cell Carcinoma in an Elderly Woman: A Diagnostic Challenge - A Case Report. Case reports in oncology 49.0 5 The unbalanced needs and perceived supply of supportive care in family caregivers of patients with multiple myeloma: a cross-sectional study. BMC palliative care 59.9 6 Development and Optimization of 111 In-Dinutuximab-IRDye800, a Dual-Modality Intraoperative Molecular Imaging Agent for Pediatric Neuroblastoma Resection. bioRxiv : the preprint server for biology 77.4 7 High-Resolution Subtyping of Pediatric Low-Grade Glioma Using an Integrated Meta-Clustering Framework. bioRxiv : the preprint server for biology 67.5 8 Concordance of rapid whole genome and targeted long read sequencing of pediatric brain tumors with standard clinical testing. Research square 61.9 9 Synergistic targeting of EP300/CBP and EYA co-activators collapses the rhabdomyosarcoma core regulatory circuit. bioRxiv : the preprint server for biology 57.6 10 Clinical Presentation of, Treatment Approaches for, and the Impact of Social Determinants of Health on Pediatric Catatonia: A Structured Qualitative Synthesis and Targeted Literature Review. Cureus 66.04 11 Sequential Philadelphia-Positive Pre-B Acute Lymphoblastic Leukemia and Chronic Myeloid Leukemia With Distinct BCR::ABL1 Fusion Transcripts. Cancer reports (Hoboken, N.J.) 67.1 12 Intracranial germ cell tumours presenting with AVP deficiency and evolving panhypopituitarism: diagnostic pitfalls in early imaging and biopsy. Endocrinology, diabetes & metabolism case reports 64.0 13 A Subset of FOXO1-Fusion Negative Rhabdomyosarcoma With Round Cell (Alveolar) and "Burkitt-Like" Morphology Is Associated With High Amplification of MYCL: A Report From the Children's Oncology Group. Genes, chromosomes & cancer 57.5 14 Pediatric lynch-associated melanoma arising in ovarian teratoma: a case report. Gynecologic oncology reports 55.1 15 Case Report: Case series: growth hormone replacement for severe growth hormone deficiency during BRAF inhibitor therapy in pediatric low-grade glioma: long-term follow-up. Frontiers in endocrinology 70.3 16 Prognostic value of lymph node ratio in children with wilms tumor: a systematic review and meta-analysis. Frontiers in oncology 79.6 17 Real-world efficacy and safety of efgartigimod in patients with autoimmune encephalitis: a single-center retrospective analysiss. Frontiers in immunology 69.1 18 Combined aromatherapy and music or sound for emotional distress: a systematic review of controlled studies published between 2019 and 2026. Frontiers in psychology 84.84 19 Longitudinal follow-up of autoimmune neutropenia in adults-a single-cohort experience. Frontiers in immunology 69.8 20 A spectrum of tumorigenesis in an IDH1-mosaic patient with Ollier disease, acute myeloid leukaemia, and parathyroid adenoma. Frontiers in genetics 57.0 21 From armed-conflict to care: clinical outcomes, diagnostic challenges, and psychosocial burden in children evaluated for suspected cancer displaced from Gaza and treated at a regional center of excellence. Frontiers in oncology 68.2 22 Clinical and radiological features of posterior reversible encephalopathy syndrome in children: a retrospective study. Frontiers in pediatrics 69.3 23 Case Report: Cytomegalovirus-associated granulomatous lung disease in an immunocompetent preterm infant. Frontiers in immunology 47.5 24 Atypical echocardiographic phenotype of end-stage hypertrophic cardiomyopathy: a case series. Frontiers in cardiovascular medicine 57.0 25 Utilizing BRAF/MEK Inhibitors to Reduce Morbidity in a Pediatric Patient With Ameloblastoma: A Case Report. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 55.26 26 EWSR1-FLI1 expression combined with monoallelic EWSR1 depletion is associated with mitotic spindle damage and nocodazole sensitivity. Biology open 53.3 27 Real-World Outcomes of Total Body Irradiation versus Chemotherapy-Based Conditioning in Pediatric Acute Lymphoblastic Leukemia. Clinical epidemiology 74.84 28 Structure and Function of Archaeal SRP54 Protein Mutants Associated with Human Severe Congenital Neutropenia. ACS omega 55.0 29 Minibeam Radiotherapy in Pediatric Cancer: First Clinical Use in a Treatment-Refractory Sarcoma. Pediatric blood & cancer 58.3 30 Refractory Idiopathic Infantile Pyoderma Gangrenosum Successfully Treated With Infliximab: A Case Report. Case reports in pediatrics 61.72 31 Prospective evaluation of serum methotrexate pharmacokinetics following intrathecal methotrexate in acute lymphoblastic leukaemia. British journal of haematology 62.8 32 Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia. Nature biomedical engineering 64.16
PATIENT-FRIENDLY SUMMARY

Not Too Young to Understand: Meaning Making From the Perspectives of School-Aged Children With Cancer-A Scoping Review.

For education only—not personal medical advice.

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