[Treatment of severe recurrent laryngotracheal papillomatosis with tracheobronchial stent].
The record describes a severe recurrent laryngotracheal papillomatosis case in which airway patency was reportedly achieved using a Y-shaped tracheobronchial stent together with adjuvant bevacizumab.
Open original publication →What the AI sees
The record describes a severe recurrent laryngotracheal papillomatosis case in which airway patency was reportedly achieved using a Y-shaped tracheobronchial stent together with adjuvant bevacizumab.
Research significance
The reported case supports feasibility of combined mechanical airway stabilization and bevacizumab in severe recurrent disease; it can only be inferred—not established—that this approach might provide rescue or palliation for selected patients whose airway obstruction is inadequately controlled by surgery.
Source abstract
Recurrent respiratory papillomatosis is a chronic airway disease that occurs in both children and adults. It is caused by the human papillomavirus, more than 90% by HPV types 6 and HPV 11. The clinical presentation is nonspecific and most patients present with hoarseness, stridor or dyspnea. Although there is no definitive treatment, the objective focuses on improving voice quality and maintaining airway patency, in our case it was achieved through the placement of a Y-shaped stent placed in airway added to adjuvant treatment with Bevacizumab. Surgical management is the mainstay of treatment and around 20% of patients benefit from adjuvant therapies.