← Back to all signals
RESEARCH PAPER ANALYSIS

Does the Initial Source of Recognition-Clinician versus Caregiver-Affect the Age at Orchidopexy for Undescended Testis? A Retrospective Comparative Analysis of 283 Cases.

In a retrospective series of 283 orchidopexy patients, surgery generally occurred well after the recommended 18-month threshold, while clinician-recognized cases underwent surgery earlier than caregiver-recognized cases, including in a pediatric-only sensitivity analysis.

Open original publication →
PMID42676546
JournalJournal of clinical practice and research
Publication Date2026-08-17
Ingested2026-09-03 09:15 AM
EXECUTIVE SUMMARY

What the AI sees

In a retrospective series of 283 orchidopexy patients, surgery generally occurred well after the recommended 18-month threshold, while clinician-recognized cases underwent surgery earlier than caregiver-recognized cases, including in a pediatric-only sensitivity analysis.

WHY IT MATTERS

Research significance

The record provides observational evidence that clinician recognition is associated with earlier orchidopexy; it is reasonable but unproven to hypothesize that strengthened primary-care screening and caregiver education could improve guideline adherence and potentially reduce long-term testicular complications, including cancer risk.

ABSTRACT

Source abstract

OBJECTIVE: To evaluate institutional adherence to international guidelines regarding the timing of treatment for undescended testis (UDT) and investigate the impact of the initial source of recognition on age at orchidopexy. MATERIALS AND METHODS: We conducted a retrospective analysis of 283 patients who underwent orchidopexy for UDT between 2012 and 2022. Chronological age, laterality, and the initial source of recognition (clinician vs. primary caregiver) were evaluated using IBM SPSS Statistics, version 28. Variables were compared using the chi-square test, independent-samples t-test, or Mann-Whitney U test, with statistical significance defined as p<0.05. RESULTS: The mean age at orchidopexy was 4.8±5.6 years, reflecting an overall trend toward delayed consultation. A subgroup analysis of 185 patients with documented recognition data showed that caregiver-detected cases underwent surgery at a significantly older age than clinician-detected cases (5.08±4.98 vs. 3.57±3.68 years; p=0.020). A sensitivity analysis excluding adult patients confirmed that this difference remained significant within the pediatric cohort (p=0.016). However, most procedures in both groups were performed well beyond the recommended 18-month guideline threshold. CONCLUSION: Delayed orchidopexy remains a prevalent clinical challenge with potential long-term implications for testicular health. Although clinician-led detection significantly improves surgical timing compared with caregiver recognition, systemic improvements in early primary care screening and caregiver awareness are essential to ensure strict adherence to optimal surgical timelines.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 [The role of neuroprotection in treating oculomotor neuropathy in a child following endoscopic cystocisternostomy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 57.6 2 Rivaroxaban prophylaxis and catheter-related thrombosis risk in ambulatory gynecological cancer patients: a retrospective cohort study. Thrombosis journal 76.9 3 Mesenchymal transition as a potential mechanism of late immune evasion in neuroblastoma: a case of late relapse after allogeneic hematopoietic stem cell transplantation. World journal of surgical oncology 88.37 4 Gold Nanoparticles in Retinoblastoma: A Promising Approach for Diagnosis and Treatment. Ocular oncology and pathology 76.5 5 Pars Plana Vitrectomy for Retinal Detachment or Vitreous Haemorrhage after Retinoblastoma Regression: A 20-Year Single-Centre Experience. Ocular oncology and pathology 63.1 6 A Novel Protein Corona-Based Secretome Profiling Assisting Cell Multiomics Analysis. Analytical chemistry 49.7 7 Trefoil Family Factor 1 Expression in the Indian Cohort of Treatment-Naïve Retinoblastoma. Ocular oncology and pathology 66.14 8 mTOR inhibitor everolimus versus conventional chemotherapy in pediatric low-grade gliomas. American journal of cancer research 83.3 9 The scPagwas analysis of single-cell sequencing combined with Bayesian deconvolution with SMR Reveals Tumor Heterogeneity and Predicts Immunotherapy Response in Neuroblastoma. Journal of Cancer 67.34 10 Early Prediction of Cardiomyopathy in Pediatric Cancer Survivors Using Echocardiographic Video-Based Deep Learning. Echocardiography (Mount Kisco, N.Y.) 57.5 11 Novel Compound Heterozygous RECQL4 Pathogenic Variants and Associated Phenotypes in a Chinese Patient With Rothmund-Thomson Syndrome: Case Report and Literature Review. Molecular genetics & genomic medicine 47.5 12 Self-Conscious Emotions and Social Isolation Among Young Adult Cancer Survivors. Psycho-oncology 66.0 13 Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with renal cell carcinoma. ESMO open 71.84 14 Fertility preservation counselling in women with cancer: knowledge, preferences, and unmet needs from a cross-sectional survey. Frontiers in endocrinology 66.1 15 Risk prediction model for pegaspargase-associated severe coagulopathy and blood product costs: a single-center retrospective cohort study. Frontiers in pharmacology 63.9 16 The relationship between symptoms of adenomyosis and current ultrasonographic diagnostic criteria. Frontiers in endocrinology 62.4 17 Feasibility of exercise training to address corticosteroid-induced changes in adolescents aged 10+ with lymphoma or leukemia during the first eight weeks of treatment: a pilot study. Frontiers in pediatrics 82.84 18 A predictive model for cytarabine syndrome-associated febrile episodes in children with acute lymphoblastic leukemia. Frontiers in pediatrics 67.4 19 The role of personalised medicine in treating high-risk neuroblastoma in paediatric patients. Oncology reviews 74.0 20 Incidence, severity, and risk factors of platinum-induced ototoxicity in pediatric oncology patients: A multi-center retrospective study. International journal of pediatric otorhinolaryngology 80.72 21 Intracranial Extension of Pott's Puffy Tumor in a Child: CT and MRI Findings. Revista da Sociedade Brasileira de Medicina Tropical 28.5 22 Detecting Isolated Multifocal Leptomeningeal Metastases With 18F-MFBG PET/CT in a Pediatric Patient With High-risk Neuroblastoma. Clinical nuclear medicine 56.4 23 Unusual Isolated Thymic Relapse of Neuroblastoma Detected By 123I-mIBG Scintigraphy in a Pediatric Patient. Clinical nuclear medicine 55.62 24 A Tale of 3 Tracers: Contrasting Uptake Patterns of 18F-FDG, 68Ga-DOTATATE, and 18F-MFBG in a Pediatric Neuroblastoma Patient. Clinical nuclear medicine 57.1 25 Clinical Diagnostic and Prognostic Evaluation of miR-136-5p in Children with Severe Pneumonia: A Case-Control and Cohort Study. Journal of visualized experiments : JoVE 70.8 26 Parents' and health professionals' perspectives on supporting physical activity among children undergoing cancer treatment: A qualitative interview study. European journal of oncology nursing : the official journal of European Oncology Nursing Society 62.74 27 Tests of the testes: markers of testicular function after treatment for pediatric hematological malignancies. The Journal of clinical endocrinology and metabolism 50.74 28 Checkpoint blockade before allogeneic transplantation in pediatric lymphoma warrants a dedicated safety strategy. Comment on: "Immune checkpoint therapy in pediatric and adolescent lymphomas". Haematologica 52.74 29 Forty-Two Cases of Pediatric Giant Cell Tumor of Bone: Insights From a 25-Year Multi-Institutional Cohort. Journal of pediatric orthopedics 63.1 30 Impact of Childbearing and Breastfeeding on Breast Density Change, and Subsequent Breast Cancer Risk in Postmenopausal Women: A Mediation Analysis. International journal of cancer 58.4 31 Neuropathological findings in 2068 individuals with drug-resistant epilepsy based on updated classification systems: A multicenter retrospective cohort study from China. Epilepsia 65.16 32 Clinical Impact of Busulfan Pharmacokinetic Monitoring in Pediatric Allogeneic Transplants: Perspectives from A Transplant Center in A Low- and Middle- Income Country. Pediatric hematology and oncology 63.4
PATIENT-FRIENDLY SUMMARY

Does the Initial Source of Recognition-Clinician versus Caregiver-Affect the Age at Orchidopexy for Undescended Testis? A Retrospective Comparative Analysis of 283 Cases.

For education only—not personal medical advice.

Before you continue

AI-assisted research information

Neurocompute uses AI to summarize scientific papers, interpret research signals, and suggest relevant reference links. AI-generated content can be incomplete, misleading, or wrong, and generated links may be irrelevant or unavailable.

Our reviewed outputs have performed strongly to date, but past accuracy is not a guarantee. Verify summaries, scores, claims, and links against the original publication before relying on them.

This platform is for research and education only. It does not provide medical advice, diagnosis, treatment recommendations, or clinical guidance.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic