← Back to all signals
RESEARCH PAPER ANALYSIS

Wilms Tumor, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.

AI interpretation is pending for this paper.

Open original publication →
PMID40763792
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Publication Date2025-08-01
Ingested2026-08-02 12:05 AM
EXECUTIVE SUMMARY

What the AI sees

Not AI summarized yet.

WHY IT MATTERS

Research significance

Pending deeper interpretation.

ABSTRACT

Source abstract

The NCCN Clinical Practice Guidelines (NCCN Guidelines) for Wilms Tumor (WT; nephroblastoma) cover strategies for the screening, diagnosis, and treatment of WT, which is the most frequent primary kidney tumor in children. WT can generally be separated into 2 histology types: favorable histology WT and anaplastic WT. Five-year survival is high for children with favorable histology WT who receive appropriate treatment; however, survival rates are much lower for patients who present with higher stage diffuse anaplastic WT. Treatment of WT can range from surgery alone to surgery plus intensive chemotherapy and radiation depending on whether the tumor is unilateral or bilateral, histology, and local stage. The goal of therapy is to maximize cure while minimizing long-term toxicities. The content featured in this issue covers the NCCN panel's recommendations for overall management of both favorable histology WT and anaplastic WT.

SUPPORTING PAPER SET

32 more papers to review

Ranked by current scoring engine
1 Assessment of suffering in Tunisian adolescents with sarcoma: A descriptive study. Canadian oncology nursing journal = Revue canadienne de nursing oncologique 59.5 2 Donor lymphocyte infusion as immune modulation after pediatric allogeneic transplantation. Blood immunology & cellular therapy 68.6 3 Exploratory quantitative magnetic resonance imaging characterization of histopathologic subtype heterogeneity in osteosarcoma. Polish journal of radiology 62.9 4 Contrasting relapse rate associated with the absence of HLA-A3/A11 in T cell-replete haploidentical transplantation. Frontiers in immunology 67.72 5 Development of a stacked ensemble model for risk stratification of chronic GVHD after allogeneic HSCT: Japanese nation-wide cohort study. Frontiers in immunology 70.3 6 Limited discriminant validity of health belief and 3C models in high HPV vaccine coverage settings: the moderating role of hukou and structural barriers. Frontiers in public health 63.7 7 Nationwide utilization patterns and perioperative outcomes of minimally invasive pediatric nephrectomy in Germany. Frontiers in pediatrics 64.9 8 Correction: Coexisting PTEN and SDHB mutations in a pediatric patient with PTEN hamartoma tumor syndrome: a case report. Frontiers in pediatrics 41.0 9 Therapeutic ecology of the fiber-microbiota-barrier axis in leukemia: resilience, immune recovery and pharmacomicrobiomics. Frontiers in microbiology 74.0 10 Social media mediation in adolescent and young adult cancer experiences: a qualitative study integrating lived and clinical perspectives. European journal of oncology nursing : the official journal of European Oncology Nursing Society 56.0 11 CNS Involvement in Paediatric AML Patients: Real-world Data from a Tertiary Care Center. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 77.1 12 Restricted Anthracycline Strategy in Pediatric Acute Promyelocytic Leukemia - A Single Centre Experience. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 70.1 13 Clinical Profile and Outcomes of Pediatric Secondary HLH: Insights from a Tertiary Care Hospital. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 63.5 14 Pure Red Cell Aplasia in a Tropical Setting: A Comprehensive Etiological Profiling of the Largest Cohort from South Asia. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 57.6 15 Preharvest Platelet Counts Predict Response To Plerixafor in Pediatric Patients Undergoing Autologous Stem Cell Transplant. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 74.62 16 Askin Tumor Presents with Ewing Sarcoma of the Femur in Young Female Patient: Case Report and Literature Review. Journal of orthopaedic case reports 57.8 17 Osteoblastoma of the Hamate: A Case Report. Journal of orthopaedic case reports 49.0 18 Hybrid Prosthetic and Biological Reconstruction Using Extracorporeal Radiotherapy for Long-Segment Humeral Osteosarcoma: A Case Report. Journal of orthopaedic case reports 55.44 19 Paediatric Pedunculated Dorsal Osteochondroma of the Scapula: A Medical Oddity with Review of Literature. Journal of orthopaedic case reports 49.0 20 Pediatric Cervical Spine Aneurysmal Bone Cyst with Recurrent Atlantoaxial Rotatory Subluxation Requiring C1-C2 Fusion: A 7-Year Follow-Up Case Report. Journal of orthopaedic case reports 53.8 21 Proximal Tibial Giant Cell Tumor in a Skeletally Immature Child: A Diagnostic Dilemma and Review of the Literature. Journal of orthopaedic case reports 47.5 22 Limb Salvage for Entire Tibial Ewing Sarcoma in a 4-year-Old Child Using Extracorporeal Irradiation and Free Flap Reconstruction: A Case Report and Surgical Technique. Journal of orthopaedic case reports 54.3 23 Addition of Rituximab to First-Line Treatment of Burkitt Lymphoma in Children and Young Adults in Tanzania: A Cost-Utility Analysis. JCO global oncology 72.14 24 Real-World Efficacy and Safety of Tyrosine Kinase Inhibitors in Patients With Advanced Bone Sarcomas: The TOGBONE Study of the Turkish Oncology Group. JCO global oncology 83.36 25 Long intramural left coronary artery confined to the left sinus of Valsalva with diastolic deformation: a case report. European heart journal. Case reports 47.5 26 Dual-modality imaging with CEUS and MRI for early recurrence assessment in hepatocellular carcinoma following combined radiofrequency ablation and transarterial chemoembolization. Frontiers in oncology 69.4 27 The impact of ready-to-use-therapeutic-food (RUTF) on micronutrient levels in undernourished children with cancer: a randomized open-labelled controlled study. European journal of clinical nutrition 72.54 28 Germline Cancer Predisposition and De Novo Contributions in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group. International journal of cancer 62.5 29 The lifelong transcriptomic landscape of human blood cells. Protein & cell 57.2 30 Bibliometric and Knowledge-Mapping Analysis of Sacrococcygeal Pilonidal Disease Research (2000-2025). Journal of visualized experiments : JoVE 57.5 31 Outcomes of acute lymphoblastic leukemia in children and young adults treated with a Berlin-Frankfurt-Münste-based protocol in a tertiary care multispecialty government hospital. Indian journal of cancer 67.8 32 Recurrent C19MC-altered embryonal tumors with multilayered rosettes: outcomes of stereotactic radiosurgery. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 66.7
PATIENT-FRIENDLY SUMMARY

Wilms Tumor, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.

For education only—not personal medical advice.

Pediatric cancer research intelligence graphic
PEDIATRIC CANCER VISUAL SYSTEM

Open the Research Intelligence Map

Explore the active pediatric oncology analysis view.

Expand Intelligence View →
Full Pediatric cancer research intelligence graphic